Migraine diagnosed before pregnancy is associated with adverse outcomes during pregnancy

Women are disproportionately affected by migraines, especially during their childbearing years. However, the relationship between migraine and adverse pregnancy outcomes has not been well understood. A new study conducted by investigators from Brigham and Women’s Hospital, a founding member of General Brigham and General Healthcare System, analyzed data from thousands of women from the Nurses’ … Read more

Genotyping technology may help increase the number of kidney transplants and reduce waiting times

ABO blood type compatibility between organ donors and recipients is critical for safe transplants. Across different ABO blood groups, patients with ABO blood type often experience longer waiting times, resulting in fewer donors. Type B blood type is more prevalent among blacks and Asians. African Americans are more likely to request kidney transplants than other … Read more

The study showed that the integrity of the brain-computer interfaces is similar to other implanted neurodevices

For people with paralysis caused by a neurological injury or disease—such as ALS (also known as Lou Gehrig’s disease), stroke, or spinal cord injury—; Brain-computer interfaces (BCIs) have the ability to restore connectivity, movement, and independence by transmitting information directly from the brain to a computer or other assistive technology. Although implanted brain sensors, the … Read more

A comprehensive atlas of protein isases can help scientists decipher many cellular signaling pathways

One of the most important classes of human enzymes are protein kinases – ; Signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism. Dysfunction in these cellular pathways can lead to a variety of diseases, particularly cancer. Identification of protein enzymes involved in cellular dysfunction and cancer development could lead … Read more

The simple method increases the effectiveness of T cell therapy by means of cell conjugation

Recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T-cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and instilled in greater numbers back into the circulation. To help fight cancer. In the successful version of ACT … Read more

Insilico Medicine launches sixth generation smart drug discovery laboratory

Insilico Medicine (“Insilico”), a clinical stage, artificial intelligence (AI) based drug discovery company, held a Life Star – a 6 launch ceremonyThe tenth Generation of intelligent drug discovery robotics lab – at BioBAY Suzhou Industrial Park on Dec. 29. The fully automated, AI-powered robotics laboratory performs target discovery, compound screening, precision medicine development, and translational … Read more

Zebrafish could provide genetic clues for the evolution of social behaviors in humans, the domesticated species

Researchers at Queen Mary University of London have shown that zebrafish can provide genes baz1b Evidence for the evolution of social behaviors in humans and domesticated species. Research published in iScienceI looked at transgenic zebrafish that fail to make baz1b protein. The results indicate that the gene is not only at the center of physical … Read more

A deep learning tool identifies mosaic mutations that cause disease

Genetic mutations cause hundreds of unsolved and untreatable disorders. Among them, DNA mutations in a small percentage of cells, called mosaic mutations, are very difficult to detect because they are present in only a small percentage of cells. While examining the 3 billion bases of the human genome, current DNA mutation detectors are not well … Read more